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KMID : 1011920140150040021
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International Journal of Arrhythmia
2014 Volume.15 No. 4 p.21 ~ p.26
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On Young-Keun
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Abstract
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Atrial fibrillation (AF), whether paroxysmal, persistent, or permanent, and whether symptomatic or silent, significantly increases the risk of thromboembolic ischemic stroke. Non-valvular AF increases the risk of stroke 5 times and AF in the setting of mitral stenosis increases the risk of stroke 20 times over patients in sinus rhythm. Thromboembolism occurring with AF is associated with a greater risk of recurrent stroke, more severe disability, and mortality. The CHA2DS2-VASc score is recommended for thromboembolic risk evaluation in nonvalvular AF. HAS-BLED score is recommended for bleeding risk evaluation. Careful consideration is required to balance the benefits and the risks of bleeding of anticoagulation in each individual patient.
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KEYWORD
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atrial fibrillation, anticoagulation, warfarin, new oral anticoagulant
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